Best VCs for Biotech

Co-Founder & Partner

Founders Fund

The original contrarian VC. 'We wanted flying cars, instead we got 140 characters.' Seeks companies that can become category-defining monopolies in markets others ignore. First principles thinking is

Founder

Khosla Ventures

Explicitly optimizes for ~70% failure rates to back 'black swan' outcomes. Actively seeks opportunities that appear 'crazy' to most of the market. Capital-intensive, science-heavy bets. Believes fusio

CEO & President

Y Combinator

Builder-designer-investor. 'Make something people want' is the entire thesis — inherited from Paul Graham's YC founding philosophy and now amplified by Garry's builder ethos. Believes we're in a golde

Co-Founder & Managing Partner

Lux Capital

'Atoms, not bits.' The biggest opportunities are in companies that manipulate the physical world, not just software. Willing to fund multi-year R&D timelines. Just raised the firm's largest fund ever

Founder

Gil Capital (Solo GP)

One of the largest and most successful solo GP funds ever ($1B+). Unusually dense hit rate across breakout companies — has invested in more unicorns than most institutional funds. Invests based on pat

Partner, Capital Formation

Lux Capital

Kalish’s role at Lux is centered on capital formation rather than direct investing. Lux says he focuses on building long-term investor relationships grounded in transparency and trust, and on helping