Best VCs for DeFi

CIO

Nascent

CIO at Nascent, managing the fund's liquid and venture portfolio across crypto markets.

Co-Founder

Nascent

Co-founded Nascent as a crypto-native fund investing in DeFi and infrastructure. Thesis-driven with a focus on protocols that create new financial primitives.

Founding Partner

Woodstock Fund

Woodstock Fund is one of India's earliest crypto-native VCs. Focuses on infrastructure, DeFi, and projects with global reach but India connections. Early backers of Polygon.

Founding Partner

Woodstock Fund

Woodstock Fund invests in blockchain infrastructure from India. Early backers of Polygon and other Indian-origin crypto projects.

Co-Founder

Maven 11 Capital

European crypto investing. DeFi, infrastructure, and zero-knowledge proofs.

Co-founder

Hash CIB

Investing in crypto infrastructure and digital assets through Hash CIB, one of Russia/CIS's most established crypto financial firms.

Co-Founder & Managing Partner

Delphi Ventures

Co-founder of Delphi Digital and Delphi Ventures. Thesis-driven investing informed by deep crypto research and data analysis.

Partner / Head of Delphi Labs

Delphi Ventures

Investing in DeFi and crypto infrastructure at Delphi Ventures. Focuses on technical evaluation of protocols and smart contract systems.

Co-Founder & Managing Partner

Delphi Ventures

DeFi research, crypto analytics, and investment analysis. Co-founded Delphi Digital.

Partner / Head of Ventures

Delphi Ventures

Crypto research and quantitative analysis. Focus on tokenomics and protocol design.

Partner

Framework Ventures

DeFi researcher and investor at Framework Ventures. Deep quantitative approach to evaluating DeFi protocols and their economic sustainability.

Principal

Framework Ventures

Investing in DeFi and crypto infrastructure at Framework Ventures. Focuses on protocols that expand the design space of decentralized finance.

General Partner

Dragonfly

Early-stage crypto investor at Dragonfly with deep DeFi expertise. Focuses on novel financial primitives and infrastructure that expands what's possible in decentralized finance.

Principal

Dragonfly

Investing in crypto infrastructure and DeFi at Dragonfly. Focused on the intersection of technology and narrative in crypto markets.

General Partner

Framework Ventures

DeFi-native investor at Framework Ventures. Focuses on programmable finance and novel DeFi protocols that create new financial primitives.

Managing Partner

Dragonfly

Infrastructure, DeFi, and crypto gaming. Clear thinking and good writing.

Co-Founder & General Partner

Framework Ventures

DeFi, gaming, consumer crypto. High-conviction bets and active portfolio support.

Co-Founder & General Partner

Framework Ventures

DeFi governance and token economics. Active DeFi governance participant.

Co-Founder & Managing Partner

Multicoin Capital

Thesis-driven investing. Crypto as coordination layer for the internet. Fat protocol thesis. Early Solana bull. DePIN evangelist.

Co-Founder & Managing Partner

Multicoin Capital

Open finance and tokenization. Strong views on stablecoins, DePIN, and crypto in emerging markets.

Partner

a16z Crypto

Data-driven crypto research. On-chain metrics, developer activity, ecosystem health. State of Crypto reports.

Partner

a16z Crypto

Enterprise crypto, stablecoins, RWA tokenization. Bridge between TradFi and DeFi.

Partner

Multicoin Capital

Solana ecosystem, DeFi, DePIN. High-performance blockchain applications.

Founder & Managing Partner

ParaFi Capital

DeFi infrastructure and digital asset management. Bridges institutional capital and DeFi.

Co-Founder

Greenfield Capital

Web3 infrastructure and DeFi from European perspective.

Co-Founder & Managing Partner

Blockchain Capital

Co-founded Blockchain Capital alongside his twin brother Bart. Focuses on venture-stage blockchain companies with strong management teams and clear business models.

Partner

Blockchain Capital

Investing across the crypto stack at Blockchain Capital, one of the oldest crypto-focused funds. Focuses on infrastructure and application layers of blockchain technology.

Founder, Compound & Robot Ventures

Robot Ventures

Founder-investor perspective at Robot Ventures. Deep expertise in DeFi, having built one of the most important DeFi protocols (Compound). Backs founders building foundational DeFi infrastructure.

Managing Partner

Robot Ventures

Rigorous quantitative approach to crypto investing at Robot Ventures. Applies mathematical modeling and simulation to evaluate DeFi protocols and crypto systems.

Partner

Polychain Capital

Investing in blockchain infrastructure and tokens at Polychain Capital, one of the most prominent crypto-native funds.

Co-Founder & Managing Partner

Paradigm

Backs transformative crypto protocols and infrastructure. Crypto is the most important tech revolution since the internet.

Founder & CEO

Polychain Capital

Crypto protocols are the native business model of the internet. Protocol-level investments, governance tokens, cross-chain infrastructure.

Co-Founder & Managing Partner

Paradigm

Protocol-level investments and new financial primitives. Open-source money, programmable economics, governance, mechanism design.

General Partner & Head of Research

Paradigm

DeFi mechanism design, AMM theory, MEV research. Novel financial primitives and their mathematical foundations.

Research Partner

Paradigm

Smart contract security, white hat hacking, DeFi security research.

General Partner

Paradigm

DeFi infrastructure, MEV, protocol economics. Intersection of market microstructure and blockchain design.

Partner

Polychain Capital

ZK proofs, privacy infrastructure, developer tooling. Privacy is a fundamental right and crypto's key unsolved problem.

Partner

Polychain Capital

DeFi protocols, token economics, governance design. Sustainable DeFi models.

General Partner

Blockchain Capital

Broadly focused crypto investing. One of the longest-tenured crypto VCs.

Partner

Blockchain Capital

Investment in early-stage blockchain companies and tokens.

Partner

Pantera Capital

Applies rigorous economic theory and mechanism design to crypto investing. Focuses on projects where game theory and incentive alignment are core to the value proposition.

General Partner

Pantera Capital

Investing in blockchain infrastructure and tokens at Pantera Capital. Focuses on protocol-level investments with long-term value creation potential.

Founder & CEO

Haun Ventures

Crypto regulation, compliance, and institutional adoption. Former DOJ prosecutor.

Co-Chief Investment Officer

Pantera Capital

DeFi, prediction markets, protocol design. Creator of Augur.

Managing Partner

Pantera Capital

Broadly focused crypto VC. One of the most prolific investors in the space.

Founder & CEO

Wintermute Ventures

Trading infrastructure, DeFi liquidity, and market microstructure. Wintermute is one of the largest crypto market makers.

General Partner, a16z crypto (Founder & Lead)

Andreessen Horowitz (a16z)

The crypto conviction investor. Founded and leads a16z's crypto practice, which has deployed billions across five funds. Author of 'Read Write Own' (2024), arguing that blockchain enables a new era of

Investor

Variant Fund

Investing in ownership economy and user-owned networks at Variant Fund. Believes in shifting value capture from platforms to users and contributors.

President & Chief Investment Officer

Galaxy Digital

Institutional-grade crypto investment across the full capital structure. Focuses on bridging traditional finance and digital assets.

Co-Founder & General Partner

Variant Fund

Investing in the ownership economy at Variant Fund. Pioneer of on-chain data analysis for crypto investment decisions. Believes data-driven analysis is key to identifying the best crypto investments.

VP Corporate Development

Coinbase Ventures

Leads Coinbase Ventures, one of the most prolific corporate crypto investors. Invests broadly across the crypto ecosystem to grow the overall market and bring more assets on-chain.

Head of Galaxy Digital Research

Galaxy Digital

Growth-stage crypto investing at Galaxy Digital. Focuses on scaling proven crypto businesses and protocols into institutional-grade platforms.

Head of Galaxy Interactive

Galaxy Digital

Investing in the future of digital assets and blockchain infrastructure at Galaxy Digital. Also known for founding Blockworks, a leading crypto media company.

General Partner, Galaxy Ventures

Galaxy Digital

Invests in crypto infrastructure and DeFi protocols at Galaxy Digital. Focuses on foundational technology that enables the next wave of crypto applications.

Former President

Jump Crypto

Jump Crypto was the crypto arm of Jump Trading, one of the world's largest quantitative trading firms. Focused on building infrastructure, particularly cross-chain bridges and DeFi protocols.

Co-founder & Managing Partner

Spartan Group

Spartan Group is a multi-strategy crypto fund based in Singapore, investing in DeFi, gaming, and infrastructure across Asia and globally. Known for advisory work and token launches.

Co-founder & Managing Partner

Spartan Group

Co-leads Spartan Group's investment and advisory practice. Focus on token design, go-to-market strategy, and connecting projects to the Asian crypto ecosystem.

Co-Founder & Managing Partner

Variant Fund

Ownership economy. Users should own a stake in the networks they contribute to.

Former Head of Ventures

Solana Ventures

Former Head of Solana Ventures and FTX Ventures. Known for institutional crypto deals and ecosystem investing.

Head of Coinbase Ventures

Coinbase Ventures

Head of Coinbase Ventures, one of the most active corporate crypto investors globally. Coinbase Ventures takes a portfolio approach, investing across the entire crypto stack.

Managing Partner & Co-Founder

Electric Capital

Developer ecosystems and data-driven investing. Publishes Electric Capital Developer Report.

Founder & GP

dao5

Crypto-native fund investing in DeFi, infrastructure, and consumer crypto. Believes in the DAO-native future of organizations.

Managing Partner

Hack VC

Infrastructure, DeFi, and AI x crypto. Previously co-led Dragonfly before starting Hack VC.

CEO & Co-Founder

Arca

Digital asset management bridging traditional and crypto finance. Focus on liquid tokens and DeFi yield.

Co-founder

Mechanism Capital

Thesis-driven investing at the intersection of DeFi and trading infrastructure. Mechanism Capital focuses on DeFi protocols, derivatives, and novel financial primitives. Known for deep technical analy

Co-founder

Alliance DAO

Focuses on consumer crypto applications and protocols that drive mass adoption. Believes the next wave of crypto will be driven by consumer-facing products, not infrastructure. Alliance accelerates cr

Co-Founder & CEO

1confirmation

Concentrated, conviction-driven crypto investing. Backs projects building fundamental infrastructure for decentralized systems with a long time horizon.

Angel Investor / Writer

BitMEX Ventures

Co-founded BitMEX, pioneered crypto perpetual futures. Now runs Maelstrom fund investing in DeFi and crypto infrastructure. Known for macro-driven crypto thesis and provocative market commentary.

General Partner

1kx

Investing in early-stage crypto protocols and infrastructure at 1kx. Focused on community-owned and operated networks.

Head of Binance Labs

Binance Labs

Invests across the full web3 stack with a focus on infrastructure, DeFi, and gaming. Binance Labs serves as the venture capital and incubation arm of Binance, one of the largest crypto exchanges globa

CEO of SCB 10X

SCB 10X

SCB 10X is the venture arm of Siam Commercial Bank (SCB), Thailand's oldest bank. Invests in blockchain, DeFi, and digital assets to bridge traditional finance with crypto.

Founder & CEO

Rockaway Blockchain Fund

Rockaway Blockchain Fund invests in DeFi and infrastructure from Prague. One of Central Europe's most active crypto investors with positions in Solana, Lido, and other major protocols.

Co-founder

Kyber Ventures

Co-founded KyberSwap, one of the first decentralized exchanges. Kyber Ventures invests in DeFi and blockchain infrastructure, with deep roots in the Southeast Asian crypto ecosystem.

Investment Director

Binance Labs

Investment Director at Binance Labs, evaluating and leading investments across the Binance ecosystem.

Co-founder

Mechanism Capital

Co-founded Mechanism Capital focusing on DeFi and trading infrastructure. Combines trading experience with venture investing.

Co-Founder (Convicted)

Alameda Research

Formerly one of crypto's most prominent figures as founder of FTX and Alameda Research. Convicted of fraud in 2023.

Co-founder

Alliance DAO

Co-founded Alliance DAO as an accelerator for crypto startups. Focus on consumer crypto and DeFi applications.

Head of Ventures

Circle Ventures

Leads Circle Ventures, investing in the USDC ecosystem and projects that advance digital dollar adoption worldwide.

Founder

1confirmation

Crypto-native consumer products and decentralized governance. Pioneer crypto-native VC.

Founder & Managing Partner

Fabric Ventures

Open-source networks and web3 infrastructure.

Founding General Partner

1kx

Token-based business models and early-stage investing. One of Europe's top crypto VCs.

Founder

IOSG Ventures

Infrastructure and DeFi in both Asian and Western markets. Bridge between East and West crypto.

Founder & GP

Portal Ventures

Investing in early-stage crypto infrastructure and applications at Portal Ventures. Focused on backing technical founders building at the frontier of blockchain technology.

Managing Partner

CoinFund

Managing Partner at CoinFund, investing across the crypto stack from infrastructure to applications. Focuses on projects with novel business models enabled by tokens.

Managing Partner & Head of Liquid Investments

CoinFund

Liquid and venture crypto investing at CoinFund. Bridges the gap between liquid token markets and early-stage venture investing.

Managing Partner

CoinFund

Institutional crypto advocate and investor at CoinFund. Focuses on bridging traditional financial markets infrastructure with crypto.

CEO, HashKey Capital

Hashkey Capital

Investing in digital asset infrastructure and Web3 projects at HashKey Capital. Focuses on Asia-Pacific crypto ecosystem development.

Partner, Liquid Fund & Research

Hashkey Capital

Blockchain research and investment at HashKey Capital. Brings rigorous research methodology to evaluating crypto projects across the APAC region.

Director of Investment

Hashkey Capital

Investing in blockchain and digital asset projects at HashKey Capital with a focus on the Greater China and Southeast Asian crypto ecosystem.

Founder & CEO

DFG (Digital Finance Group)

Founded DFG to invest in blockchain infrastructure and digital assets globally. Bridges Eastern and Western crypto ecosystems with a focus on protocol-level investments.

Executive Director

DFG (Digital Finance Group)

Executive leadership at DFG focused on scaling blockchain investment operations and portfolio management across global crypto markets.

Investment Director

DFG (Digital Finance Group)

Investing in early-stage blockchain projects at DFG with a focus on DeFi, infrastructure, and emerging crypto ecosystems.

Co-Founder

Archetype

Focuses on open network builders and new market structures. Believes in backing founders building protocol-level infrastructure and novel token economic models that create entirely new markets.

Founder

Colosseum

Investing in the Solana ecosystem at Colosseum, the organization behind Solana hackathons. Focused on discovering and nurturing early-stage Solana builders.

Angel / Researcher

Crypto researcher and investor with deep expertise in on-chain data analysis. Known for detailed research on DeFi protocols and market microstructure.

Co-Founder

Lemniscap

Investing in blockchain infrastructure and digital assets at Lemniscap, with a focus on European and global crypto ecosystem development.

Managing Partner

Cypher Capital

Investing in blockchain and digital assets across the MENA region at Cypher Capital. Focused on building Dubai as a global crypto hub.

Managing Partner

Hashed Emergent

Investing in blockchain projects across South and Southeast Asia at Hashed Emergent. Focused on crypto adoption in emerging markets.

Founder & CEO

ConsenSys

Building the decentralized future on Ethereum. ConsenSys is both a software company and a venture studio, creating foundational Ethereum infrastructure including MetaMask, Infura, and Linea.

Investment Partner

OKX Ventures

Leading blockchain investments at OKX Ventures, the investment arm of one of the world's largest crypto exchanges. Focuses on projects that expand the OKX ecosystem.

Partner

Eden Block

Investing in early-stage blockchain projects at Eden Block, with a focus on European crypto ecosystem development and infrastructure.

Head of Investments

GSR Markets

Leading crypto market making and trading operations at GSR Markets, with a strategic investment arm backing infrastructure and DeFi projects.

Partner

Italian Angels for Growth (Web3)

Investing in blockchain and Web3 startups in Italy through the Italian Angels for Growth network. Focused on bringing Italian innovation to the global crypto stage.

Partner

Black Pearls VC

Investing in blockchain and tech startups in Central and Eastern Europe through Black Pearls VC, focused on regional ecosystem development.

Founder

QDAO DeFi

Focused on DeFi infrastructure and decentralized governance through QDAO DeFi, investing in projects that advance financial decentralization.

Head of SEA & MENA

BNB Chain MVB (Central Asia)

Supporting blockchain innovation in Central Asia through BNB Chain's MVB program. Focused on growing the BNB Chain ecosystem in underserved markets.

Co-founder

Shorooq Partners

Investing in early-stage tech and blockchain startups across MENA at Shorooq Partners. Focused on digital infrastructure and fintech for the Arab world.

Co-founder & Partner

AirTree Ventures (Web3)

Investing in Web3 and blockchain projects in the Australian and APAC startup ecosystem through AirTree Ventures, one of Australia's top VC firms.

Co-founder

Crypto.com Capital

Strategic investments from Crypto.com Capital, the investment arm of one of the world's largest crypto platforms. Focused on ecosystem expansion and strategic portfolio building.

Managing Partner

Platanus Ventures

Investing in early-stage tech and blockchain startups in Chile and Latin America through Platanus Ventures, bringing Silicon Valley VC practices to LATAM.

GP

Ethereal Ventures

Academic turned crypto investor, bringing rigorous economic thinking to token design and mechanism design. Ethereal Ventures invests in crypto projects with strong economic foundations.

Co-founder

Zee Prime Capital

Zee Prime Capital is a remote-first crypto fund investing in infrastructure and DeFi. Known for deep technical analysis and early Solana ecosystem conviction.

Founder & CEO

CV VC

CV VC invests in blockchain companies from Crypto Valley (Zug, Switzerland). Focus on enterprise blockchain, L1 protocols, and Swiss crypto ecosystem development.

Founder of OKX Ventures

OKX Ventures

OKX Ventures invests in blockchain infrastructure, DeFi, and Web3 globally. As the venture arm of OKX exchange, focuses on projects that advance the open and decentralized web.

Senior Investment Principal, Hivemind Capital Partners

Hivemind Capital

Phillips's overarching thesis is bridging the on-chain and off-chain worlds, primarily through market infrastructure — the 'unsexy backbone' of stablecoins, settlement rails, custody, tokenization, an

Managing Partner

Newtown Partners

Newtown Partners invests in blockchain companies across Africa and globally from Cape Town. Early backers of Luno and VALR, two of Africa's largest crypto exchanges.

Founding Partner

NGC Ventures

NGC Ventures invests in blockchain infrastructure, DeFi, and Web3 applications. One of the earliest institutional crypto funds in Asia, with a portfolio spanning 100+ projects.

Founding Partner

Fenbushi Capital

Fenbushi Capital was one of the first China-based blockchain VCs, founded in 2015 with Vitalik Buterin as an advisor. Invests broadly across blockchain infrastructure and applications.

General Partner

Fenbushi Capital

General Partner at Fenbushi, focusing on infrastructure and DeFi investments. Bridges Western and Asian crypto ecosystems.

Co-founder & CEO

Bitso Ventures

Bitso is Mexico's and Latin America's leading crypto exchange. Bitso Ventures invests in crypto and fintech across Latin America.

Founder

Dialectic

Dialectic is a crypto-native fund focused on DeFi and infrastructure. Known for deep involvement in protocol governance and early Polkadot ecosystem.

Partner, Web3

Northzone (Web3)

Leads Northzone's web3 investments from Stockholm. Northzone is one of Europe's top VCs, and Wendy brings a crypto-native lens to their portfolio.

Co-founder & CEO

Bitpanda Ventures

Bitpanda is Europe's leading digital asset platform. Bitpanda Ventures invests in crypto and fintech across Europe from Vienna.

Managing GP

Indico Capital

Indico Capital invests in tech and crypto from Lisbon. Helping build Portugal's reputation as a crypto-friendly European hub.

Founder & CEO

Daftar (Web3)

Daftar invests in tech and web3 across South Asia and MENA. One of the few funds bridging Pakistan's tech talent with global crypto opportunities.

Co-founder & CEO

MultiversX Capital

Built MultiversX (formerly Elrond) as a sharded L1 blockchain. MultiversX Capital invests in projects building on the MultiversX ecosystem.

Founding Partner

Shorooq Partners

Shorooq Partners invests in MENA fintech and crypto. Leading the charge on web3 adoption in the UAE, Saudi Arabia, and broader Middle East.

Founding Partner

Africa Blockchain Fund

Africa Blockchain Fund invests in blockchain projects across Africa from Ghana. Focuses on financial inclusion and real-world blockchain applications for African markets.

Co-founder & Partner

AirTree Ventures (Web3)

AirTree is one of Australia's top VCs, with a dedicated web3 thesis. Invests in blockchain infrastructure and gaming, including early backing of Immutable and Fantom.

Angel Investor

Crypto as the native money of the internet. Believes in Bitcoin and Ethereum as protocols for digital money and digital trust.

Co-founder & CEO

Amber Group

Amber Group combines crypto trading, lending, and venture investing. One of Asia's largest digital asset platforms.

Co-founder & CEO

Centrality

Centrality builds blockchain infrastructure from New Zealand. Focus on making blockchain accessible for mainstream applications.

Founder & Managing Partner

SNZ Holding

SNZ Holding invests in blockchain infrastructure and DeFi from Shanghai. Active in Polkadot and cross-chain ecosystems.

Head of Venture

Superscrypt

Superscrypt is Temasek's crypto venture arm, investing in blockchain infrastructure from Singapore.

General Partner

Reciprocal Ventures

Reciprocal Ventures invests in web3 infrastructure and applications.

Co-founder

SevenX Ventures

Co-founded SevenX Ventures focused on blockchain infrastructure and ZK technology from Asia.

Head of Ventures

Kraken Ventures

Leads Kraken Ventures, the investment arm of Kraken exchange. Invests in infrastructure and DeFi.

Founder & CEO

Distributed Global

Distributed Global invests in blockchain from Estonia, one of Europe's most digitally advanced nations.

CEO Tokocrypto

Tokocrypto Ventures

Tokocrypto is Indonesia's leading crypto exchange. Tokocrypto Ventures invests in web3 projects targeting Southeast Asian markets.

Founding Partner

NGC Ventures

NGC Ventures co-founding partner. One of the earliest institutional blockchain investors in Singapore.

CEO

CMT Digital

CMT Digital is the crypto venture arm of CMT Group, a proprietary trading firm. Invests in infrastructure, DeFi, and digital asset trading.

Managing Director

North Island Ventures

North Island Ventures invests in crypto and fintech at the intersection of traditional and decentralized finance.

Founding Partner

SevenX Ventures

SevenX Ventures invests in crypto infrastructure and DeFi from Asia. Focus on ZK technology and cross-chain solutions.

Chairman & Partner

AppWorks

AppWorks is Taiwan's leading accelerator and VC, with a dedicated web3 track. Investing in blockchain startups across Southeast Asia.

Investment Associate

Adaverse

Adaverse invests in blockchain projects building on Cardano across Africa. Focus on financial inclusion and real-world blockchain applications.

Co-founder & Chairman

Matrixport

Co-founded Bitmain, the world's largest Bitcoin mining hardware manufacturer. Now leads Matrixport, a digital asset financial services platform.

Founder of Terra (Convicted)

Formerly the creator of Terra/Luna, focused on algorithmic stablecoins and DeFi infrastructure. Currently facing legal proceedings related to Terra's collapse.

Angel / Founder

Solana founder. Believes in high-performance monolithic blockchains over modular approaches.

Founder & CEO

CoinFund

Web3 infrastructure, data markets, and token-based business models.

Co-Founder

Standard Crypto

Crypto infrastructure and network formation. Focus on how crypto networks bootstrap.

Angel Investor

Crypto-native angel investor. Focuses on DeFi, NFTs, and onchain culture. Known for early Ethereum ecosystem bets.

Angel / Writer

Crypto data infrastructure and the institutionalization of digital assets.

Founder & GP

Shima Capital

Early-stage crypto investing across DeFi, gaming, infrastructure. Believes in backing technical founders building for the long term.

Angel / Founder

Solana co-founder. Focus on business development and ecosystem growth.

Partner

Lightspeed Faction

Crypto infrastructure and applications. Focus on the next generation of crypto-native companies.

Angel Investor / Creator

Consumer crypto, memecoins, and crypto culture. One of the most influential crypto personalities.

Angel / Advisor

Bitcoin and institutional crypto investment thesis.

Co-Founder & General Partner

Lattice Fund

Former Head Economist & CMO, ConsenSys

ConsenSys

Principal

Blockwall VC

At Blockwall, Armani invests within a pre-seed and seed Web3 strategy focused on the infrastructure and applications shaping a transparent, secure digital future. His profile and writing point to part