Best VCs for DeFi
388 venture capitalists actively investing in DeFi.
CIO
Nascent
CIO at Nascent, managing the fund's liquid and venture portfolio across crypto markets.
39 deals
Co-Founder
Nascent
Co-founded Nascent as a crypto-native fund investing in DeFi and infrastructure. Thesis-driven with a focus on protocols that create new financial primitives.
39 deals
Venture Investor
Nascent
39 deals
Partner
Maven 11 Capital
Darius works within Maven 11's crypto-native, early-stage strategy. The firm backs technically fluent founders who challenge the status quo by redefining ownership through open, inclusive, permissionl
16 deals
Associate Partner
Maven 11 Capital
Pim applies bioinformatics, data-science and machine-learning training to fundamental crypto investing. His disclosed lead investments span decentralized AI compute, zero-knowledge proof systems, tran
16 deals
Sr Associate Operations
Woodstock Fund
Woodstock publicly describes itself as a thesis- and research-driven Web3 investment firm investing in early and growth stage companies and protocols. Its published thesis centers on three megatrends:
16 deals
Founding Partner
Woodstock Fund
Woodstock Fund is one of India's earliest crypto-native VCs. Focuses on infrastructure, DeFi, and projects with global reach but India connections. Early backers of Polygon.
16 deals
Founding Partner
Woodstock Fund
Woodstock Fund invests in blockchain infrastructure from India. Early backers of Polygon and other Indian-origin crypto projects.
16 deals
Investment Partner
Woodstock Fund
Woodstock describes itself as a thesis- and research-driven Web 3.0 investment firm investing in early- and growth-stage companies and protocols. Its published thesis is organized around three megatre
16 deals
Venture Partner (US)
Woodstock Fund
Based on Woodstock Fund's published thesis, the firm is a thesis- and research-driven Web3 investor backing early- and growth-stage companies and protocols. Its thesis is organized around three megatr
16 deals
Co-Founder
Maven 11 Capital
European crypto investing. DeFi, infrastructure, and zero-knowledge proofs.
16 deals
Research Associate
Woodstock Fund
16 deals
Co-founder
Hash CIB
Investing in crypto infrastructure and digital assets through Hash CIB, one of Russia/CIS's most established crypto financial firms.
10 deals
Co-Founder & Managing Partner
Delphi Ventures
DeFi research, crypto analytics, and investment analysis. Co-founded Delphi Digital.
8 deals
Partner / Head of Ventures
Delphi Ventures
Crypto research and quantitative analysis. Focus on tokenomics and protocol design.
8 deals
Partner / Head of Delphi Labs
Delphi Ventures
Investing in DeFi and crypto infrastructure at Delphi Ventures. Focuses on technical evaluation of protocols and smart contract systems.
8 deals
Co-Founder & Managing Partner
Delphi Ventures
Co-founder of Delphi Digital and Delphi Ventures. Thesis-driven investing informed by deep crypto research and data analysis.
8 deals
Principal
Framework Ventures
Investing in DeFi and crypto infrastructure at Framework Ventures. Focuses on protocols that expand the design space of decentralized finance.
7 deals
Managing Partner
Dragonfly
Infrastructure, DeFi, and crypto gaming. Clear thinking and good writing.
7 deals
Co-Founder & General Partner
Framework Ventures
DeFi, gaming, consumer crypto. High-conviction bets and active portfolio support.
7 deals
General Partner
Dragonfly
Early-stage crypto investor at Dragonfly with deep DeFi expertise. Focuses on novel financial primitives and infrastructure that expands what's possible in decentralized finance.
7 deals
Co-Founder & General Partner
Framework Ventures
DeFi governance and token economics. Active DeFi governance participant.
7 deals
General Partner
Framework Ventures
DeFi-native investor at Framework Ventures. Focuses on programmable finance and novel DeFi protocols that create new financial primitives.
7 deals
Partner
Framework Ventures
DeFi researcher and investor at Framework Ventures. Deep quantitative approach to evaluating DeFi protocols and their economic sustainability.
7 deals
Principal
Dragonfly
Investing in crypto infrastructure and DeFi at Dragonfly. Focused on the intersection of technology and narrative in crypto markets.
7 deals
Liquid Portfolio Analyst
Dragonfly
7 deals
Research Analyst
Placeholder
7 deals
Investment Partner
a16z crypto
Liz focuses on the picks-and-shovels and decentralized infrastructure that let crypto mature into useful, open economic systems. Her authored investment work emphasizes market infrastructure for incre
6 deals
Co-Founder & Managing Partner
Multicoin Capital
Thesis-driven investing. Crypto as coordination layer for the internet. Fat protocol thesis. Early Solana bull. DePIN evangelist.
6 deals
Managing Partner
Multicoin Capital
Open finance and tokenization. Strong views on stablecoins, DePIN, and crypto in emerging markets.
6 deals
Partner
a16z crypto
Data-driven crypto research. On-chain metrics, developer activity, ecosystem health. State of Crypto reports.
6 deals
General Partner, Co-Head of Venture
Multicoin Capital
Solana ecosystem, DeFi, DePIN. High-performance blockchain applications.
6 deals
Partner
a16z crypto
Enterprise crypto, stablecoins, RWA tokenization. Bridge between TradFi and DeFi.
6 deals
Partner, Head of Investor Relations
Multicoin Capital
6 deals
Investing Partner
a16z crypto
6 deals
Research Partner
Greenfield Capital
Felix uses research and market data to identify durable crypto infrastructure and distinguish fundamental adoption from speculation. His work favors protocols with measurable usage, revenue or value a
5 deals
Partner and Chief Operating Officer
Greenfield Capital
Christian applies transaction, regulatory, and policy expertise to executing Greenfield's crypto investments. His work argues for clear decentralization standards, practical token tax treatment, open
5 deals
Principal
Greenfield Capital
Claude leads Greenfield's consumer investing and backs crypto products that turn mature onchain rails into understandable, trusted consumer experiences. His published work focuses on mobile-native DeF
5 deals
Principal
ParaFi Capital
Josh focuses on blockchain infrastructure that can replace costly financial plumbing and connect digital assets to large, existing pools of economic activity. His public work highlights stablecoins fo
5 deals
Principal
Greenfield Capital
Gleb leads Greenfield's DeFi work, combining protocol research, infrastructure operating experience, and deal execution. His current research emphasizes capital-efficient and safer liquidity architect
5 deals
Partner
ParaFi Capital
Kevin approaches digital assets as both a quantitative portfolio manager and a systems builder. His remit joins non-directional and fundamental market strategies with production technology, while his
5 deals
Associate
ParaFi Capital
Jono's public work points to investable digital-asset opportunities where on-chain rails make familiar assets globally accessible and more liquid. He tracks tokenized equities and collectibles through
5 deals
Founder & Managing Partner
ParaFi Capital
DeFi infrastructure and digital asset management. Bridges institutional capital and DeFi.
5 deals
Co-Founder
Greenfield Capital
Web3 infrastructure and DeFi from European perspective.
5 deals
Partner
Polychain Capital
Investing in blockchain infrastructure and tokens at Polychain Capital, one of the most prominent crypto-native funds.
4 deals
Former Investor, Blockchain Capital (off current roster)
Blockchain Capital
In his Blockchain Capital work, Sterling focused on the intersection of consumers and crypto. He saw gaming as a mass-onboarding path because persistent games, interoperable assets and player-owned ec
4 deals
Partner, Investing & Research
Paradigm
Alpin partners with crypto founders and researchers who have strong instincts about the future and the courage to follow them. His work centers on protocol, market, and mechanism design—especially sys
4 deals
Co-Founder & Managing Partner
Paradigm
Protocol-level investments and new financial primitives. Open-source money, programmable economics, governance, mechanism design.
4 deals
General Partner & Head of Research
Paradigm
DeFi mechanism design, AMM theory, MEV research. Novel financial primitives and their mathematical foundations.
4 deals
VENTURE PARTNER
Blockchain Capital
Lucas specializes in rebuilding credit and capital markets on shared blockchain infrastructure. His operating record points to tokenized funds, real-world assets, institutional DeFi, and end-to-end le
4 deals
Investor
Blockchain Capital
Jonah studies where value and power accrue as crypto infrastructure matures. He argues that open rails can unbundle closed payment networks; user-owning applications can compress infrastructure margin
4 deals
Founder & CEO
Polychain Capital
Crypto protocols are the native business model of the internet. Protocol-level investments, governance tokens, cross-chain infrastructure.
4 deals
Co-Founder & Managing Partner
Paradigm
Backs transformative crypto protocols and infrastructure. Crypto is the most important tech revolution since the internet.
4 deals
Investor
Blockchain Capital
Jonah studies where value and power accrue as crypto infrastructure matures. He argues that open rails can unbundle closed payment networks; user-owning applications can compress infrastructure margin
4 deals
Partner
Blockchain Capital
Yuan backs crypto-native founders with earned insight, behavioral resilience, learning velocity, and the ability to translate non-consensus ideas into enduring systems. His technical work spans modula
4 deals
General Partner
Blockchain Capital
Broadly focused crypto investing. One of the longest-tenured crypto VCs.
4 deals
General Partner
Paradigm
DeFi infrastructure, MEV, protocol economics. Intersection of market microstructure and blockchain design.
4 deals
Partner
Blockchain Capital
Investment in early-stage blockchain companies and tokens.
4 deals
Founder, Compound & Robot Ventures
Robot Ventures
Founder-investor perspective at Robot Ventures. Deep expertise in DeFi, having built one of the most important DeFi protocols (Compound). Backs founders building foundational DeFi infrastructure.
4 deals
Co-Founder & Managing Partner
Blockchain Capital
Co-founded Blockchain Capital alongside his twin brother Bart. Focuses on venture-stage blockchain companies with strong management teams and clear business models.
4 deals
Managing Partner
Robot Ventures
Rigorous quantitative approach to crypto investing at Robot Ventures. Applies mathematical modeling and simulation to evaluate DeFi protocols and crypto systems.
4 deals
Partner
Polychain Capital
ZK proofs, privacy infrastructure, developer tooling. Privacy is a fundamental right and crypto's key unsolved problem.
4 deals
Partner
Polychain Capital
DeFi protocols, token economics, governance design. Sustainable DeFi models.
4 deals
Research Partner
Paradigm
Smart contract security, white hat hacking, DeFi security research.
4 deals
Partner
Blockchain Capital
Investing across the crypto stack at Blockchain Capital, one of the oldest crypto-focused funds. Focuses on infrastructure and application layers of blockchain technology.
4 deals
Junior Partner
Pantera Capital
Joey treats blockchain as a permissionless, composable technology stack for programming value and human behavior—not merely a digital copy of traditional finance. He is looking for institutional DeFi
3 deals
Founder & CEO
Haun Ventures
Crypto regulation, compliance, and institutional adoption. Former DOJ prosecutor.
3 deals
Principal
Haun Ventures
Mark combines smart-contract and token-incentive building experience with early-stage investing. Current evidence favors useful crypto businesses rather than hype, particularly institutional market in
3 deals
Principal
Haun Ventures
Mark combines a builder's understanding of smart contracts and token incentives with early-stage investing. Current evidence points to founders building useful crypto businesses rather than chasing ma
3 deals
Co-founder
Wintermute Ventures
Yoann brings high-frequency trading, hedge-fund and family-office experience to a proprietary-capital venture platform built around Wintermute's market infrastructure. The firm backs category-defining
3 deals
Managing Partner
Pantera Capital
Broadly focused crypto VC. One of the most prolific investors in the space.
3 deals
General Partner
Pantera Capital
Investing in blockchain infrastructure and tokens at Pantera Capital. Focuses on protocol-level investments with long-term value creation potential.
3 deals
Co-Chief Investment Officer
Pantera Capital
DeFi, prediction markets, protocol design. Creator of Augur.
3 deals
Partner
Pantera Capital
Public evidence supports a Pantera-wide, not Matt-specific, mandate: multi-stage blockchain venture and token exposure with follow-on capital for companies that demonstrate product-market fit. Matt's
3 deals
Partner
Pantera Capital
Applies rigorous economic theory and mechanism design to crypto investing. Focuses on projects where game theory and incentive alignment are core to the value proposition.
3 deals
Founder & CEO
Wintermute Ventures
Trading infrastructure, DeFi liquidity, and market microstructure. Wintermute is one of the largest crypto market makers.
3 deals
General Partner, a16z crypto (Founder & Lead)
Andreessen Horowitz (a16z)
The crypto conviction investor. Founded and leads a16z's crypto practice, which has deployed billions across five funds. Author of 'Read Write Own' (2024), arguing that blockchain enables a new era of
2 deals
VP Corporate Development
Coinbase Ventures
Leads Coinbase Ventures, one of the most prolific corporate crypto investors. Invests broadly across the crypto ecosystem to grow the overall market and bring more assets on-chain.
2 deals
Research Partner
Hack VC
Peyman treats confidentiality as market infrastructure rather than an abstract right. His research uses identity-based encryption and distributed decryption to prevent front-running with dramatically
2 deals
Co-Founder & Managing Partner
Variant Fund
Ownership economy. Users should own a stake in the networks they contribute to.
2 deals
Managing Partner & Co-Founder
Electric Capital
Developer ecosystems and data-driven investing. Publishes Electric Capital Developer Report.
2 deals
Investment Partner
Variant Fund
Elijah backs technically ambitious founders building new mechanisms, markets and infrastructure. His work joins crypto market design with a widening AI thesis: mature financial systems need expressive
2 deals
Co-founder & Managing Partner
The Spartan Group
Spartan Group is a multi-strategy crypto fund based in Singapore, investing in DeFi, gaming, and infrastructure across Asia and globally. Known for advisory work and token launches.
2 deals
Former President
Jump Crypto
Jump Crypto was the crypto arm of Jump Trading, one of the world's largest quantitative trading firms. Focused on building infrastructure, particularly cross-chain bridges and DeFi protocols.
2 deals
Partner
Hack VC
Rodney backs technical infrastructure that removes adoption bottlenecks for high-value crypto use cases. His work favors modular, open AI stacks that solve data, compute and availability; stablecoin c
2 deals
Investor
Electric Capital
Sanjay's stated remit is liquid crypto portfolio management across trading and DeFi strategies. His combination of consulting, company-building and graduate technical/business training suggests an ope
2 deals
Partner
Hack VC
Herbie invests at the intersection of crypto, AI and productive infrastructure. His GAIB thesis treats compute as a scarce commodity that can become an investable, yield-producing on-chain asset, fina
2 deals
Co-founder & Managing Partner
The Spartan Group
Co-leads Spartan Group's investment and advisory practice. Focus on token design, go-to-market strategy, and connecting projects to the Asian crypto ecosystem.
2 deals
Investor
Electric Capital
Trevor applies a long quantitative-investing background to Electric's engineer-led frontier-technology mandate. His prior roles across multi-strategy, retirement, institutional asset-management and in
2 deals
Co-Founder & General Partner
Variant Fund
Investing in the ownership economy at Variant Fund. Pioneer of on-chain data analysis for crypto investment decisions. Believes data-driven analysis is key to identifying the best crypto investments.
2 deals
Head of Galaxy Interactive
Galaxy Digital
Investing in the future of digital assets and blockchain infrastructure at Galaxy Digital. Also known for founding Blockworks, a leading crypto media company.
2 deals
President & Chief Investment Officer
Galaxy Digital
Institutional-grade crypto investment across the full capital structure. Focuses on bridging traditional finance and digital assets.
2 deals
General Partner, Galaxy Ventures
Galaxy Digital
Invests in crypto infrastructure and DeFi protocols at Galaxy Digital. Focuses on foundational technology that enables the next wave of crypto applications.
2 deals
Managing Partner
Hack VC
Infrastructure, DeFi, and AI x crypto. Previously co-led Dragonfly before starting Hack VC.
2 deals
Former Head of Ventures
Solana Ventures
Former Head of Solana Ventures and FTX Ventures. Known for institutional crypto deals and ecosystem investing.
2 deals
Head of Coinbase Ventures
Coinbase Ventures
Head of Coinbase Ventures, one of the most active corporate crypto investors globally. Coinbase Ventures takes a portfolio approach, investing across the entire crypto stack.
2 deals
Head of Galaxy Digital Research
Galaxy Digital
Growth-stage crypto investing at Galaxy Digital. Focuses on scaling proven crypto businesses and protocols into institutional-grade platforms.
2 deals
Investor
Variant Fund
Investing in ownership economy and user-owned networks at Variant Fund. Believes in shifting value capture from platforms to users and contributors.
2 deals
Founder & GP
dao5
Crypto-native fund investing in DeFi, infrastructure, and consumer crypto. Believes in the DAO-native future of organizations.
2 deals
CEO & Co-Founder
Arca
Digital asset management bridging traditional and crypto finance. Focus on liquid tokens and DeFi yield.
2 deals