Best VCs for Machine Learning

26 venture capitalists actively investing in Machine Learning.

26

Active VCs

0

Funds

0

Deals

Partner

Khosla Ventures

Alex invests where computation, biology, and healthcare converge. His scientific and clinical background supports a systems view of biomarker discovery, therapeutics, diagnostics, personalized medicin

No personal check range is published. Khosla's Seed Fund supports science and business-model experiments, historically often with roughly $1M–$2M according to a 2020 firm interview, while its Main Fund covers early through later stages. These are firm-level references, not Alex's authority.

IncubationPre-SeedSeed

General Partner

Y Combinator

David's founder story centers on building a simple mobile product to massive reach, confronting weak long-term retention and monetization honestly, then following the strongest user behavior into a be

YC's current standard deal is $500K for each accepted company: $125K for 7% on a post-money SAFE plus $375K on an uncapped MFN SAFE, accompanied by YC's participation right. It is a program-wide deal, not David's personal angel range.

IdeaPre-SeedBatch-stage startup

Investor

First Round Capital

Maggie's documented lens is research depth: she respects founders who do the work required to understand a problem at first principles and prefers to dig alongside them. Her technical background in si

First Round's published firm-wide initial checks are typically $1M–$7M, averaging about $3.5M; it has participated in rounds from $100K to $20M. No personal range or signing authority is published for Maggie.

AngelPre-SeedSeed

Managing Partner

Y Combinator

Diana works with technical founders building frontier AI, robotics and hard technology. Her Escher Reality and Niantic experience combines zero-to-one infrastructure with deployment at consumer scale,

YC's live standard deal is $500K per accepted company: $125K on a post-money SAFE for 7% plus $375K on an uncapped MFN SAFE, with a participation right. This is YC's standardized program deal, not Diana's personal check range.

IdeaPre-SeedBatch-stage startup

#5Leah Mitchell

Chief of Staff

Differential Ventures

Leah Mitchell is listed in a Chief of Staff capacity at Differential Ventures. The firm does not publish a person-specific investment thesis for this role; this profile preserves that role distinction

$250K-$3M initial investments, as published by Differential Ventures.

Partner

ParaFi Capital

Kevin approaches digital assets as both a quantitative portfolio manager and a systems builder. His remit joins non-directional and fundamental market strategies with production technology, while his

No personal venture check range is disclosed. Kevin leads quantitative strategies and technology development inside a multi-strategy manager spanning public and private markets; founders should not infer a standard venture ticket or sole decision authority from the Partner title.

Liquid MarketsQuantitative StrategiesPublic Markets

Venture Partner

Differential Ventures

Allen Duan invests or supports investments through Differential Ventures's published strategy: Back data-centric B2B founders at pre-seed and seed building applied AI, machine-learning, engineering an

$250K-$3M initial investments, as published by Differential Ventures.

Chief Financial Officer

Differential Ventures

Lloyd Appel is listed in a Chief Financial Officer capacity at Differential Ventures. The firm does not publish a person-specific investment thesis for this role; this profile preserves that role dist

$250K-$3M initial investments, as published by Differential Ventures.

#9Jeremy Kirsch

Operating Partner

Differential Ventures

Jeremy Kirsch invests or supports investments through Differential Ventures's published strategy: Back data-centric B2B founders at pre-seed and seed building applied AI, machine-learning, engineering

$250K-$3M initial investments, as published by Differential Ventures.

#10Geoff Harris

Managing Partner

Flying Fish Ventures

Geoff Harris invests or supports investments through Flying Fish Ventures's published strategy: Partner at pre-seed and seed with founders using AI and machine learning to build foundational infrastru

Flying Fish Ventures does not publish a standard current check-size range on its official site.

#11Heather Redman

Managing Partner

Flying Fish Ventures

Heather Redman invests or supports investments through Flying Fish Ventures's published strategy: Partner at pre-seed and seed with founders using AI and machine learning to build foundational infrast

Flying Fish Ventures does not publish a standard current check-size range on its official site.

Managing Partner

Flying Fish Ventures

Frank Chang invests or supports investments through Flying Fish Ventures's published strategy: Partner at pre-seed and seed with founders using AI and machine learning to build foundational infrastruc

Flying Fish Ventures does not publish a standard current check-size range on its official site.

#13Heather Gorham

Venture Partner

Flying Fish Ventures

Heather Gorham invests or supports investments through Flying Fish Ventures's published strategy: Partner at pre-seed and seed with founders using AI and machine learning to build foundational infrast

Flying Fish Ventures does not publish a standard current check-size range on its official site.

#14Tiffany Linke-Boyko

Principal

Flying Fish Ventures

Tiffany Linke-Boyko invests or supports investments through Flying Fish Ventures's published strategy: Partner at pre-seed and seed with founders using AI and machine learning to build foundational in

Flying Fish Ventures does not publish a standard current check-size range on its official site.

#15Adriane Brown

Managing Partner

Flying Fish Ventures

Adriane Brown invests or supports investments through Flying Fish Ventures's published strategy: Partner at pre-seed and seed with founders using AI and machine learning to build foundational infrastr

Flying Fish Ventures does not publish a standard current check-size range on its official site.

Chief Financial Officer

Flying Fish Ventures

Tri Tran is listed in a Chief Financial Officer capacity at Flying Fish Ventures. No person-specific investment thesis is published for this role; the firm's mandate is included only as shared context

Flying Fish Ventures does not publish a standard current check-size range on its official site.

#17Malyun Abdullahi

Chief of Staff

Flying Fish Ventures

Malyun Abdullahi is listed in a Chief of Staff capacity at Flying Fish Ventures. No person-specific investment thesis is published for this role; the firm's mandate is included only as shared context.

Flying Fish Ventures does not publish a standard current check-size range on its official site.

Venture Partner

Flying Fish Ventures

Lisa Nelson invests or supports investments through Flying Fish Ventures's published strategy: Partner at pre-seed and seed with founders using AI and machine learning to build foundational infrastruc

Flying Fish Ventures does not publish a standard current check-size range on its official site.

#19Vanessa Pegueros

Venture Partner

Flying Fish Ventures

Vanessa Pegueros invests or supports investments through Flying Fish Ventures's published strategy: Partner at pre-seed and seed with founders using AI and machine learning to build foundational infra

Flying Fish Ventures does not publish a standard current check-size range on its official site.

Managing Partner

Differential Ventures

Nick Adams invests or supports investments through Differential Ventures's published strategy: Back data-centric B2B founders at pre-seed and seed building applied AI, machine-learning, engineering an

$250K-$3M initial investments, as published by Differential Ventures.

#21David Magerman

Managing Partner

Differential Ventures

David Magerman invests or supports investments through Differential Ventures's published strategy: Back data-centric B2B founders at pre-seed and seed building applied AI, machine-learning, engineerin

$250K-$3M initial investments, as published by Differential Ventures.

#22Tom Driscoll

Principal

Differential Ventures

Tom Driscoll invests or supports investments through Differential Ventures's published strategy: Back data-centric B2B founders at pre-seed and seed building applied AI, machine-learning, engineering

$250K-$3M initial investments, as published by Differential Ventures.

Associate

Differential Ventures

Tina Vinod invests or supports investments through Differential Ventures's published strategy: Back data-centric B2B founders at pre-seed and seed building applied AI, machine-learning, engineering an

$250K-$3M initial investments, as published by Differential Ventures.

Partner

Khosla Ventures

Jon focuses on how machine learning reshapes the full enterprise stack: core infrastructure, developer tools, and end-user applications. His experience as an early Palantir engineer, infrastructure fo

Not publicly disclosed. Khosla Ventures uses a Seed Fund for experiments and a Main Fund for early-to-later rounds, including financings above $10M in total round size; round size is not the firm's or Jon's check size.

Pre-SeedSeedSeries A

Partner

Lux Capital

Lan is a Lux generalist with a defined intersection across computation and biology: computational analytics in biotech and healthcare, data and ML infrastructure, platform therapeutics, developer tool

Firm-level: Lux says it can invest from an initial $100K through high-conviction follow-ons as large as $100M across the company-building arc. This is not Lan's personal standard check range.

InceptionPre-SeedSeed

Partner, Capital Formation

Lux Capital

Kalish’s role at Lux is centered on capital formation rather than direct investing. Lux says he focuses on building long-term investor relationships grounded in transparency and trust, and on helping

Explore more sectors

All Sectors Machine Learning Investments All VCs